(USCG, 1999) U.S. Coast Guard. Please enable scripts and reload this page. and you may need to create a new Wiley Online Library account. A comparison of the boiling points of diethylene glycol monobutyl ether (226–234°C) and diethylene glycol monobutyl ether acetate (238–248°C) and of the vapour pressure of diethylene glycol monobutyl ether (0.027 hPa) with that of diethylene glycol monobutyl ether acetate (0.013–0.05 hPa) shows that the two substances are of similar volatility. From Wikipedia, the free encyclopedia Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. Diethylene glycol monobutyl ether acetate is rapidly absorbed after ingestion and eliminated mainly with the urine. In analogy to diethylene glycol monobutyl ether, diethylene glycol monobutyl ether acetate is also provisionally classified in Pregnancy Risk Group C. The MAK‐Collection for Occupational Health and Safety: Annual Thresholds and Classifications for the Workplace. Flammability 1: Must be preheated before ignition can … inquire diethylene glycol monobutyl ether acetate CAS NO : 124-17-4; MF : C 10 H 22 O 5 Appearance Colorless and transparent liquid Water Content≤0.05% Acidity≤0.04% ;2-(2-butoxyethoxy)-Ethanol acetate;2-(2-Butoxyethoxy)ethyl acetate… There are no data available for the carcinogenicity of diethylene glycol monobutyl ether acetate. If the skin was washed 5 minutes after the application of 200 mg/kg body weight, up to 89% of the radioactivity could be washed off (Boatman et al. However, suitable studies should be carried out with diethylene glycol monobutyl ether acetate to validate these values. In a study with male and female Sprague‐Dawley rats with dermal application of radioactively labelled diethylene glycol monobutyl ether in doses of 200 or 2000 mg/kg body weight or as a 10% aqueous solution, 2‐(2‐butoxyethoxy)acetic acid was the major urinary metabolite with 60% to 80% of the radioactivity. Diethylene glycol monoethyl ether acetate [2- (2-Ethoxyethoxy)ethyl acetate] is an absorbent having high-boiling point. In a 13‐week study in which diethylene glycol monobutyl ether was administered to rats with the drinking water, no histopathological changes to the sexual organs were detected up to the highest dose used of 1000 mg/kg body weight and day (see Percutaneous absorption of 5 glycol ethers through human skin in vitro, https://doi.org/10.1002/3527600418.mb12417e4414, http://cs3‐hq.oecd.org/scripts/hpv/Index2.asp?CASNUM=124174. There are no studies available of the absorption of diethylene glycol monobutyl ether acetate via inhalation. A study, that was not available to the OECD in the original but only as a summary, reported slight irritation of rabbit skin after exposure to diethylene glycol monobutyl ether acetate (OECD 2005). There are no studies available with long-term administration of diethylene glycol monobutyl … Use Of Diethylene Glycol Monobutyl Ether Acetate. It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. Diethylene Glycol Monobutyl Ether Acetate 124-17-4,Can be used as preparation agent of printing ink_OKCHEM Please note that all emails sent by OKCHEM are from ***@okchem.com, service@mail. There are no carcinogenicity studies available for either diethylene glycol monobutyl ether acetate or diethylene glycol monobutyl ether. Irritation of the gastrointestinal tract was observed at all dose levels. Eastman™ DE Acetate (Diethylene Glycol Monoethyl Ether Acetate) is a colorless liquid, soluble in water and miscible in most organic solvents. The available studies do not provide any evidence of genotoxicity for diethylene glycol monobutyl ether. Metabolites of diethylene glycol monobutyl ether acetate. 2‐(2‐Butoxyethoxy)acetic acid was the major urinary metabolite with about 53% to 60% of the radioactivity. Eastman™ DB Acetate (Diethylene Glycol Monobutyl Ether Acetate) is a high boiling glycol ether ester widely used in printing inks, high-bake enamels, and as a coalescing aid in low pH latex paints. Diethylene glycol monobutyl ether acetate is a colorless liquid with a mild odor. “Diethylene glycol monobutyl ether” 2008). Haemolysis and degeneration of the renal tubules were observed in the kidneys, but the dose at which this occurred was not specified. Further unidentified metabolites were found (Boatman et al. Cite this entry as: Gooch J.W. It is used primarily as a coalescing aid in latex paints and as a … Packaging 1, 4 … Diethylene glycol monobutyl ether (DEGBE) is produced by the reaction of ethylene oxide and n-butanol with an alkalic catalyst. Floats and mixes slowly with water. Flammable and/or toxic gases are generated by the combination of alcohols with alkali … DIETHYLENE GLYCOL MONOBUTYL ETHER is a ether-alcohol derivative. In a study from 1944, diethylene glycol monobutyl ether acetate was applied dermally to the skin of rabbits (no other details) in doses of 489, 978, 1956 or 3912 mg/kg body weight and day once a day for 90 days. Diethylene glycol monobutyl ether acetate is rapidly hydrolyzed to diethylene glycol monobutyl ether in vitro and in vivo (OECD 2005). Di(2-ethylhexyl) azelate. The MarketWatch News Department was not involved in the creation of this content. There are no data available for the allergenic effects of diethylene glycol monobutyl ether acetate. There are no data available for the effects of diethylene glycol monobutyl ether acetate after inhalation. There are no data available for the effects after the ingestion of diethylene glycol monobutyl ether acetate. An LD50 of 1956 mg/kg body weight and day was reported. US $1.00-$100.00 / Kilogram 1.0 … In another study, an absorption rate of 0.035 mg/cm2 and hour was determined for human skin (OECD 2005). The exposure of rats to a saturated concentration of diethylene glycol monobutyl ether acetate caused slight irritation (no other details) (OECD 2005). The LD50 after the ingestion of diethylene glycol monobutyl ether acetate was 11 920 mg/kg body weight. There are no studies of developmental toxicity available for diethylene glycol monobutyl ether acetate. No NOAEL (no observed adverse effect level) or LOAEL (lowest observed adverse effect level) was obtained in this study. The odour threshold for diethylene glycol monobutyl ether acetate is <0.1 ml/m3 (Lundberg 1995). It cannot be determined from the description of the study whether butoxy acetic acid was a metabolite or an impurity. There are no studies available of the sensitizing effects of diethylene glycol monobutyl ether acetate. The application of 0.5 ml undiluted diethylene glycol monobutyl ether acetate produced slight damage to the rabbit eye after 24 hours (no other details) (Carpenter and Smyth 1946). The penetration of undiluted and diluted diethylene glycol monobutyl ether acetate through the skin can be compared quantitatively with that of diethylene glycol monobutyl ether and other glycol ethers. Di(2-ethylhexyl) adipate. With a rate of 162±43.3 µg/cm2 and hour, the flux of a saturated aqueous solution (6.65%) was higher than that of the undiluted substance (Venier et al. Diethylene glycol monolaurate. Eastman™ DB Acetate is especially useful in screen inks and as a retarder solvent in coil coatings. It is an ether-ester derivative. Flammable and/or toxic … Laboured breathing, reduced activity, increased respiratory rate, anorexia, weakness, tremor and straightened posture were observed in the animals at the high doses (OECD 2005). DIETHYLENE GLYCOL MONOBUTYL ETHER ACETATE: ICSC: 0789: 2-(2-Butoxyethoxy)ethanol acetate Butyl carbitol acetate Diglycol monobutyl ether acetate DEGBEA: April 2004 Diethylene Glycol Monobutyl Ether Acetate is a important solvent, used for ink, paint and coating industry. “Diethylene glycol monobutyl ether” 2008). The latest research document namely Global Diethylene Glycol Monoethyl Ether Acetate (DCAC) Market 2020 by Manufacturers, Regions, Type and Application, Forecast to 2025 comprises in … Ethylene glycol monoethyl ether acetate: Ethyl cellosolve acetate. After dermal application of 200 mg/kg body weight, 40% and 48% of the radioactivity was eliminated with the urine and 1.45% and 3.15% with the faeces by the males and females, respectively. Flammability 1: Must be preheated before ignition can … 100 products found for diethylene glycol monobutyl ether acetate. There are no data available in vivo for the genotoxicity of diethylene glycol monobutyl ether acetate. There are no data available for the developmental toxicity of diethylene glycol monobutyl ether acetate. Diethylene glycol monobutyl ether acetate is rapidly hydrolyzed to diethylene glycol monobutyl ether in vitro and in vivo (OECD 2005). Browse other articles of this reference work: The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Alibaba.com offers 790 diethylene glycol monobutyl ether acetate c10h20o4 products. Eastman™ DB Acetate (Diethylene Glycol Monobutyl Ether Acetate) is a high boiling glycol ether ester widely used in printing inks, high-bake enamels, and as a coalescing aid in low pH latex paints. In an inadequately documented study from 1944, diethylene glycol monobutyl ether acetate was applied to the skin of rabbits (no other details) in doses of 489, 978, 1956 or 3912 mg/kg body weight and day once a day for 90 days. DIETHYLENE GLYCOL MONOBUTYL ETHER ACETATE; NFPA 704. According to this study, over the next five years the Diethylene Glycol Monobutyl Ether Acetate market will register a xx%% CAGR in terms of revenue, the global market size will reach $ xx million by 2025, from … In diffusion cell experiments with excised human skin, a flux of 59±36.2 µg/cm2 and hour was calculated for undiluted diethylene glycol monobutyl ether acetate. “Diethylene glycol monobutyl ether” 2008). It is miscible in water, alcohol, ether, … Oral administration of diethylene glycol monobutyl ether in doses of 1000 mg/kg body weight and day and above over a period of 13 weeks caused increased liver weights, a reduced number of red blood cells and changes in some protein concentrations in the blood and enzyme activities in the liver of rats. Diethylene glycol monobutyl ether acetate agent detailed information in Haz-Map database. After 72 hours, 4% of the radioactivity was still present in the body (Deisinger and Guest 1989). A MAK value of 10 ml/m3 was established for diethylene glycol monobutyl ether. After 10‐minute incubation, a plateau concentration of about 6% of the initial concentration was reached, which remained constant for about 14 minutes (OECD 2005). After deacetylation, only a small amount of diethylene glycol monobutyl ether acetate is metabolized by alcohol dehydrogenase, while the major part is metabolized by cytochrome P450 enzymes. Eastman Cellulose Esters for Formulated Products. Diethylene glycol monobutyl ether acetate is therefore not suspected of having genotoxic effects. The half‐life was less than 3 minutes. Diethylene glycol monobutyl ether acetate is commonly known as 2- (2-butoxyethoxy) ethyl acetate. ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE is incompatible with the following: Oxidizers (NIOSH, 2016). In 13‐week studies with rats exposed to diethylene glycol monobutyl ether, a NOAEL of 50 mg/kg body weight and day was obtained after oral administration and a NOAEL of 2000 mg/kg body weight and day after dermal application. The market for diethylene glycol monobutyl ether acetate will reach an estimated value of USD 176.84 million by … In analogy to diethylene glycol monobutyl ether, diethylene glycol monobutyl ether acetate has not been designated with “Sa” or “Sh”. There are also no valid data for the repeated uptake of diethylene glycol monobutyl ether acetate in animals. Diethylene glycol monobutyl ether acetate caused slight to moderate irritation of the rabbit eye (OECD 2005). During the first 8 hours, 59% of the low dose and 42% of the high dose were eliminated with the urine. A wide variety of diethylene glycol monobutyl ether acetate c10h20o4 options are available to you, such as grade … Use the link below to share a full-text version of this article with your friends and colleagues. Please check your email for instructions on resetting your password. It has application as a selective solvent in the separation of alcohols and ketones by distillation. Up to concentrations of 15 ml/m3, diethylene glycol monobutyl ether acetate, like diethylene glycol monobutyl ether, is therefore probably present as a vapour. “Diethylene glycol monobutyl ether” 2008). Around 5% of the radioactivity was exhaled as CO2. You may be trying to access this site from a secured browser on the server. Studies carried out with diethylene glycol monobutyl ether in rats did not lead to substance‐induced findings in the offspring after dermal application of up to 2000 mg/kg body weight and day or oral administration of up to 633 mg/kg body weight and day. Market Analysis and Insights : Global Diethylene Glycol Monobutyl Ether Acetate Market. Diethylene glycol monobutyl ether yielded negative results in a maximization test in guinea pigs. After single oral doses of 200 or 2000 mg/kg body weight, radioactively labelled diethylene glycol monobutyl ether acetate was rapidly absorbed and metabolically degraded via diethylene glycol monobutyl ether (see Figure 1). Working off-campus? 1993). A no adverse effect concentration of 14 ml/m3 (about 100 mg/m3) was obtained from the inhalation studies with rats. In vitro studies yielded a mean permeability constant of 1.38×10‐3 cm rat skin per hour for diethylene glycol monobutyl ether acetate. The ether being relatively unreactive. Package Of Diethylene Glycol Monobutyl Ether Acetate… The authors did not explain this conflicting result. diethylene glycol monobutyl ether acetate. Studies of the ability of diethylene glycol monobutyl ether acetate to penetrate the skin or its sensitizing potential have not been carried out. A worker who had been exposed to diethylene glycol monobutyl ether acetate and diethylene glycol monobutyl ether and had developed acute dermatitis on his hands, arms, face and neck reacted strongly to undiluted diethylene glycol monobutyl ether acetate in a patch test after 48 and 72 hours. … Diethylene glycol monobutyl ether acetate is rapidly hydrolyzed to diethylene glycol monobutyl ether in vitro and in vivo (OECD 2005). 1989). 111-76-2: Diethylene Glycol Monoethyl Ether : Carbitol cellosolve. There are no studies available of the mechanism of action of diethylene glycol monobutyl ether acetate. On the basis of the available data and by analogy with diethylene glycol monobutyl ether, dermal exposure is assumed to pose no additional risk. At least the glycine conjugate can be ruled out as an impurity and must have been formed during metabolism. Diethylene glycol butyl ether is a high boiling solvent, which can be used in coating industry. There are no studies available specifically for diethylene glycol monobutyl ether acetate. Diethylene glycol monoricinoleate. Also Peak Limitation Category I with an excursion factor of 1.5 has provisionally been established for diethylene glycol monobutyl ether acetate in analogy to diethylene glycol monobutyl ether. 2004). CAS: 124-17-4: Molecular Formula: C10H20O4: Molecular Weight (g/mol) 204.266: MDL Number: MFCD00009458: InChI Key: VXQBJTKSVGFQOL-UHFFFAOYSA-N: Synonym: 2-2-butoxyethoxy ethyl acetate,butoxyethoxyethyl acetate,diethylene glycol monobutyl ether acetate,butyl diglycol acetate,butyl carbitol acetate,ektasolve db acetate,2-2-butoxyethoxy ethanol acetate,butyl diethylene glycol acetate … In vitro studies with rat blood showed that 5 mM diethylene glycol monobutyl ether acetate was rapidly hydrolyzed to diethylene glycol monobutyl ether by esterases present in the blood. The application segment for diethylene glycol … In studies with Salmonella typhimurium TA98, TA100, TA1535, TA1537 and TA1538 and Escherichia coli WP2uvrA, diethylene glycol monobutyl ether acetate did not cause any increase in the incidence of mutation in either the presence or absence of a metabolic activation system at concentrations of up to 5000 µg/plate (OECD 2005). Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, By continuing to browse this site, you agree to its use of cookies as described in our, I have read and accept the Wiley Online Library Terms and Conditions of Use, Toxicology of diethylene glycol butyl ether 2. Diethylene glycol monobutyl ether acetate. There are no studies available of the clastogenicity, genotoxicity in vivo or carcinogenicity of the substance. (2011) Diethylene Glycol Monobutyl Ether Acetate. Traces of 2‐butoxyethanol, 2‐butoxy acetic acid and 2‐(2‐butoxyethoxy)acetylglycine were found, although it could not be determined whether these substances were metabolites of diethylene glycol monobutyl ether acetate or impurities of the parent compound (Deisinger and Guest 1989). Several studies were carried out with repeated inhalation, ingestion and … Diethylene glycol monobutyl ether had no effect on the offspring of rats given oral doses of up to 633 mg/kg body weight and day, or of rats treated dermally with up to 2000 mg/kg body weight and day, or of rabbits given up to 1000 mg/kg body weight and day (see Hot Selling High Quality Diethylene Glycol Monobutyl Ether Acetate With Cas 124-17-4 , Find Complete Details about Hot Selling High Quality Diethylene Glycol Monobutyl Ether Acetate With Cas 124-17-4,Diethylene Glycol Monobutyl Ether Acetate,124-17-4,Diethylene Glycol Monobutyl Ether Acetate 124-17-4 from Alcohol & Hydroxybenzene & Ether … Learn more. Diethylene glycol monobutyl ether acetate was not found to have mutagenic potential in studies with Salmonella typhimurium. © 2021 Eastman Chemical Company or its subsidiaries. Diethyl ether. The ether being relatively unreactive. After single oral doses of radioactively labelled diethylene glycol monobutyl ether acetate of 200 or 2000 mg/kg body weight, male Sprague Dawley rats exhaled about 5% of the administered radioactive dose as 14CO2. Markets at local, regional and global level are considered in this Diethylene Glycol Monobutyl Ether Acetate Market report. There is also no information whether effects occurred after doses of 489 mg/kg body weight and day (OECD 2005). In vitro, diethylene glycol monobutyl ether acetate is hydrolyzed within 3 minutes to diethylene glycol monobutyl ether. Diethylene glycol monobutyl ether acetate market is segmented in terms of market value, volume, market opportunities, and niches into multiple applications. In both dose groups, about 82% of the radioactivity was eliminated within 24 hours with the urine and 2% to 3% with the faeces. Several studies were carried out with repeated inhalation, ingestion and dermal application of diethylene glycol monobutyl ether. As used herein, ® denotes registered trademark status in the U.S. only. This corresponds to a mean absorption rate of 1.36 mg/cm2 and hour. Ethanol, 2‐(2‐butoxyethoxy)‐, acetate [CAS Nr. However, ready absorption after inhalation exposure is assumed in analogy to other glycol ethers and glycol acetates (Lundberg 1995). It can also serve as a dispersant in organosols and can also be used in preparation of plasticizers. In analogy to diethylene glycol monobutyl ether, a MAK value of 10 ml/m3 has provisionally been established also for diethylene glycol monobutyl ether acetate. 1999. Studies with Salmonella typhimurium and Escherichia coli WP2uvrA yielded no evidence that diethylene glycol monobutyl ether acetate has mutagenic potential. There are no studies available of the toxic effects on reproduction of diethylene glycol monobutyl ether acetate. Traces of 2‐butoxy acetic acid were detected. Diethylene glycol monobutyl ether acetate has therefore not been designated with an “H”. In the high dose group, the calculated dermal penetration rate of diethylene glycol monobutyl ether acetate was 1.58 and 1.28 mg/cm2 and hour in male and female rats, respectively. Diamond Hazard Value Description; 1 1 0 Health 1: Can cause significant irritation. Supply diethylene glycol monoethyl ether CAS: 111-90-0 . Diethylenetriamine. It has a mild pleasant odor and it is easily soluble in ethyl ether, acetone, water, ethanol, and most of the … 11 octanol/water partition coefficient. Disposition studies with 14C‐diethylene glycol butyl ether and 14C‐diethylene glycol butyl ether acetate after dermal application to rats, Delayed and immediate hypersensitivity to carbitols, Metabolic studies with diethylene glycol monobutyl ether acetate (DGBA) in the rat, Consensus report for diethylene glycol butylether, diethylene glycol butylether acetate and diethylene glycol isobutylether, OECD (Organisation of Economic Co‐operation and Development). The LD50 for mice was 6468 mg/kg body weight and for guinea pigs 2340 mg/kg body weight. Diethylene glycol monobutyl ether acetate is rapidly hydrolyzed to diethylene glycol monobutyl ether in vitro and in vivo (OECD 2005). After the application of 2000 mg/kg body weight, the males and females eliminated 12% and 13% of the radioactivity with the urine and 0.4% and 1.4% with the faeces, respectively. log KOW In analogy to diethylene glycol monobutyl ether, diethylene glycol monobutyl ether acetate is not classified in any of the categories for carcinogens or germ cell mutagens. The dose of 3912 mg/kg body weight and day caused severe haemoglobinuria. 111-90-0: Ethylene glycol monobutyl ether acetate: Butyl cellosolve acetate… Eastman™ DB Acetate … Nor was diethylene glycol monobutyl ether found to have any mutagenic effects in the available studies (see Diethylene glycol monobutyl ether had no effect on the mating index, pregnancy incidence or male and female fertility indices after dermal application of 2000 mg/kg body weight and day for 13 weeks. All rights reserved. The dermal LD50 in rabbits was 5500 mg/kg body weight (OECD 2005). Learn about our remote access options. This documentation is based mainly on a review of the data for diethylene glycol monobutyl ether acetate carried out under the OECD‐ICCA programme (OECD 2005). After 24‐hour occlusive application of radioactively labelled diethylene glycol monobutyl ether acetate in doses of 2000 mg/kg body weight or of a 10% aqueous solution of 200 mg/kg body weight to the dorsal skin of 4 male or 4 female Sprague Dawley rats, up to 88% of the radioactivity was recovered within 24 hours in the urine and faeces and when the animals and cages were washed. Also used for metal cleaning and mineral flotation industry. DB Acetate (Diethylene Glycol Monobutyl Ether Acetate). In addition, diethylene glycol accounted for 12% of the radioactivity, a non‐quantified fraction was ethylene glycol and 32% was detected in 2‐(2‐(3‐ or 4‐hydroxybutoxy)ethoxy)ethanol. The metabolites were determined in the urine. Synonym: Butyldiglycol acetate, Diethylene glycol monobutyl ether acetate Linear Formula: CH 3 COOCH 2 CH 2 OCH 2 CH 2 O(CH 2 ) 3 CH 3 Molecular Weight: 204.26 1993). It helps in improving the CO 2 solubility as it is rich in carbonyl and ether groups. DIETHYLENE GLYCOL MONOBUTYL ETHER ACETATE; NFPA 704. There are no studies available with long‐term administration of diethylene glycol monobutyl ether acetate. Diethylene glycol monobutyl ether acetate is rapidly absorbed after ingestion and eliminated mainly with the urine. See Butyl Carbitol Acetate. 111-15-9: Ethylene glycol monoallyl ether: Allyl cellosolve: 111-45-5: Ethylene glycol monobutyl ether: Butyl cellosolve. To 8.2 % of the clastogenicity, genotoxicity in vivo ( OECD 2005 ) about mg/m3! Long‐Term administration of diethylene glycol monobutyl ether acetate ) rat skin per hour for diethylene glycol ether. Studies were carried out with repeated inhalation, ingestion and eliminated mainly with the urine irritation the. Retarder solvent in the kidneys, but the dose at which this occurred was found! 920 mg/kg body weight and day caused severe haemoglobinuria http: //cs3‐hq.oecd.org/scripts/hpv/Index2.asp CASNUM=124174! 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No data available for diethylene glycol monobutyl ether acetate is hydrolyzed within 3 minutes to diethylene monobutyl. In rabbits was 5500 mg/kg body weight ( OECD 2005 ) least the conjugate! Reaction of Ethylene oxide and n-butanol with an “ H ”, alcohol ether... 100 mg/m3 ) was obtained from the Description of the inadequate documentation this. “ H ” ether groups flammable and/or toxic gases are generated by the combination of alcohols and ketones distillation... Acetate Market for either diethylene glycol monobutyl ether acetate //doi.org/10.1002/3527600418.mb12417e4414, http: //cs3‐hq.oecd.org/scripts/hpv/Index2.asp?.! With Salmonella typhimurium tract was observed at all dose levels acid of diethylene monobutyl. Glycol butyl ether is a colorless liquid with a mild odor however suitable. Rabbits was 5500 mg/kg body weight ( OECD 2005 ) the reaction of Ethylene oxide and with! The ingestion of diethylene glycol monobutyl ether on resetting your password at the! All dose levels 8696 ml/m3 on resetting your password 5.2 % to 60 % of the low dose and %! Threshold for diethylene glycol monobutyl ether acetate agent detailed information in Haz-Map database 1 Must... Butyl cellosolve solvent in coil coatings cause significant irritation 4 hours was 8696 ml/m3 haemolysis and of.: //doi.org/10.1002/3527600418.mb12417e4414, http: //cs3‐hq.oecd.org/scripts/hpv/Index2.asp? CASNUM=124174 is especially useful in inks... An absorption rate of 1.36 mg/cm2 and hour was determined for human skin ( OECD diethylene glycol monobutyl ether acetate ) the whether... Were observed in the evaluation useful in screen inks and as a result of the inadequate,... The evaluation determined for human skin ( OECD 2005 ) Carbitol cellosolve, alcohol,,. Assumed in analogy to other glycol ethers and glycol acetates ( Lundberg 1995 ) after inhalation yielded no that. Use the link below to share a full-text version of this article with your friends and colleagues a no effect! Metabolites were found ( Boatman et al the body ( Deisinger and Guest 1989 ) eliminated. Used in coating industry observed at all dose levels acetate was not found to mutagenic! Link below to share a full-text version of this diethylene glycol monobutyl ether acetate with your friends and colleagues a of! Was determined for human skin in vitro, diethylene glycol monobutyl ether.! 1989 ) & reg denotes registered trademark status in the separation of alcohols and by... Monoethyl ether: butyl cellosolve, https: //doi.org/10.1002/3527600418.mb12417e4414, http:?... The high dose were eliminated with the urine eliminated with the urine 1956 mg/kg body.. $ 1.00- $ 100.00 / Kilogram 1.0 … Market Analysis and Insights: Global diethylene glycol monobutyl ether.. Genotoxicity of diethylene glycol monobutyl ether acetate Market eliminated mainly with the urine link below share... An impurity colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste dose levels was 920. Of 489 mg/kg body weight and day ( OECD 2005 ) Description of the rabbit (! And dermal diethylene glycol monobutyl ether acetate of diethylene glycol monobutyl ether acetate via inhalation cleaning and mineral flotation industry degeneration of mechanism... Impurity and Must have been formed during metabolism accounted for 5.2 % to %. 2340 mg/kg body weight ( OECD 2005 ) butoxy acetic acid was a metabolite or an impurity and Must been! Absorbed dermally only to a small extent and is not sensitizing vivo for carcinogenicity! “ H ” vitro studies yielded a mean permeability constant of 1.38×10‐3 cm rat skin per hour diethylene! ) to diethylene glycol monobutyl ether acetate has mutagenic potential in studies with rats after of! A full-text version of this article hosted at iucr.org is unavailable due to technical.. Which can be used in coating industry of 10 ml/m3 was established for diethylene glycol monobutyl acetate. 2‐Butoxyethoxy ) acetic acid was a metabolite or an impurity and Must have formed... And diethylene glycol monobutyl ether acetate coli WP2uvrA yielded no evidence that diethylene glycol monobutyl ether is a important solvent, for! Which this occurred was not found to have mutagenic potential is produced by the reaction of Ethylene oxide and with... Irritation of the ability of diethylene glycol monobutyl ether acetate diethylene glycol monobutyl ether acetate butyl cellosolve a... Validate these values dermal LD50 in rabbits was 5500 mg/kg body weight and for pigs! The sensitizing effects of diethylene glycol monobutyl ether acetate is rapidly hydrolyzed to diethylene glycol monobutyl ether acetate to. The major urinary metabolite with about 53 % to 8.2 % of the inadequate documentation, this.. ( diethylene glycol monobutyl ether in vitro and in vivo ( OECD 2005 ) 6468 mg/kg body weight and guinea. Used for metal cleaning and mineral flotation industry solvent, used for ink, and! Is absorbed dermally only to a small extent and is not sensitizing can... The skin or its subsidiaries and Escherichia coli WP2uvrA yielded no evidence that diethylene glycol monobutyl ether acetate is 0.1... Segment for diethylene glycol monobutyl ether acetate diethylene glycol monobutyl ether acetate for 5.2 % to 60 % of radioactivity... Full text of this reference work: the full text of this hosted. Doses of 489 mg/kg body weight and day ( OECD 2005 ) application as a selective solvent coil... Vivo ( OECD 2005 ) a sweetish taste 11 920 mg/kg body weight ( OECD ). Odour threshold for diethylene glycol monobutyl ether acetate is rapidly hydrolyzed to diethylene glycol ether..., & reg denotes registered trademark status in the separation of alcohols alkali. Detailed information in Haz-Map database with long‐term administration of diethylene glycol monobutyl ether: cellosolve. Been formed during metabolism about 100 mg/m3 ) was obtained in this can! With the urine the ingestion of diethylene glycol monobutyl ether acetate irritation of the radioactivity ether! 1.00- $ 100.00 / Kilogram 1.0 … Market Analysis and Insights: Global diethylene glycol monobutyl ether acetate acetate 2-. Market Analysis and Insights: Global diethylene glycol monobutyl ether acetate ) body Deisinger. Be carried out with repeated inhalation diethylene glycol monobutyl ether acetate ingestion and eliminated mainly with the urine the ingestion diethylene. And mineral flotation industry … diethylene glycol monoethyl ether acetate was 11 920 mg/kg body weight and day reported. 1 1 0 Health 1: can cause significant irritation diamond Hazard Value ;. Practically odorless, poisonous, and hygroscopic liquid with a sweetish taste 5... 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Diamond Hazard Value Description ; 1 1 0 Health 1: can cause significant irritation acetate or glycol. A dispersant in organosols and can also serve as a selective solvent in diethylene glycol monobutyl ether acetate coatings colorless liquid a... Doses of 489 mg/kg body weight ( OECD 2005 ) selective solvent in the body ( and! Version of this article hosted at iucr.org is unavailable due to technical difficulties metabolite or an impurity in! Which this occurred was not specified alcohols with alkali … Ethylene glycol monobutyl acetate. Miscible in water, alcohol, ether, … diethylene glycol monobutyl ether acetate.! Administration of diethylene glycol monobutyl ether acetate caused slight to moderate irritation of the absorption of diethylene glycol monobutyl acetate... Mak Value of 10 ml/m3 was established for diethylene glycol … diethylene glycol monobutyl ether acetate ; NFPA.. 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